Gout is a form of arthritis caused by a build-up of uric acid within the body, which is a waste product of metabolism.
It is more common in men aged 40-60 and symptoms normally appear suddenly. Pain, swelling, and itchiness in the big toe joint can indicate the presence of this condition.
Symptoms tend to come on very quickly and then last for around a week before easing off. They include intense pain in the joint, usually affecting the big toe and foot. The skin may appear red and shiny and there may be peeling or flaking of the skin.
The joint will be swollen and may also feel itchy. It is most common in the big toe, but may also be present in the heels, ankles, knees, elbows, wrists or fingers.
What is gout? It is more common in men although it does occur in women as well. It is most prevalent in men between the ages of 40 and 60. You are more likely to suffer if anyone in your family does as there is a genetic element involved. Risk factors also include a diet high in some meats, seafood and alcohol, particularly beer.
Certain medications such as aspirin, niacin, diuretics, and chemotherapy may also contribute to the development of the disease. It is, therefore, more common in those who suffer from high blood pressure, high cholesterol, and cancers as well as diabetes and psoriasis. Problems with the function of the kidneys or high production of uric acid may mean that crystals develop within the joints which cause pain and inflammation.
The symptoms recorded by your G.P are often used to give a clinical impression that gout is causing the pain. However, to properly diagnose the condition further tests are required:
Serum Uric Acid Tests are performed on a small sample of blood, usually taken from the arm. The test is often carried out 4-6 weeks after an attack because the serum uric acid level is often not elevated at the time symptoms are worst. A raised serum uric acid test result is an indicator that you may have this condition, although this is not 100% accurate as people without the condition may sometimes have a higher than normal levels.
Synovial Fluid is found within synovial joints and a sample can be extracted from a joint and examined under a microscope. There will almost always be crystals of sodium urate in the sample. This kind of test can also rule out other causes of joint pain.
Pain is managed by relieving the pain and treating the condition with both medication and lifestyle changes such as following a specific diet. To relieve symptoms, rest with the foot elevated and apply cold therapy to cool the joint.
Non-steroidal Anti-inflammatory drugs (NSAID’s) such as Ibuprofen can be taken in the first instance to decrease pain. If these are not effective, then your doctor may prescribe Colchicine, which helps to relieve pain and reduce swelling. It does however often produce side effects such as nausea, vomiting, and abdominal pain. In extreme cases, you may be prescribed corticosteroids, although these are not long-term treatment.
Medications for frequent attacks are known as Urate Lowering Therapies or ULT. The aim of these medications is to reduce the urate levels to below the concentration required for crystals to form. They also help to dissolve existing crystals.
There are different forms of ULT which have different effects and side-effects. Allopurinol is one of the most common. Febuxostat is another.
Lifestyle changes should also be implemented to avoid flare-ups of the condition. Eliminating or at least cutting down on the following may be helpful:
- Meats including liver, kidney, turkey, veal, and venison
- Seafood such as anchovies, mackerel, sardines, herrings, mussels, and scallops
- Vegetables including spinach, asparagus, and lentils
- Anything containing yeast extract such as Marmite
- Alcohol – particularly beers and port
Ensure you also drink plenty of water. If you are overweight, losing weight can help to decrease your uric acid levels, as can exercise.